- Studies conducted by researchers at the Centre for Cellular Molecular Biology (CCMB), CARE hospital and Osmania University has revealed that genetic mutation is responsible for heart failure in dilated cardiomyopathy.
- They compared Troponin T (cTnT) gene from the DNA of affected and normal individuals and identified a novel genetic mutation which is responsible for the disease.
- The analysis was a limited hospital-based study, and there are plans to extend it to a larger population-based study.
- Early detection of mutation of this gene could lead to early screening and medical treatment to prevent sudden cardiac death.
- Dilated cardiomyopathy is a type of cardiac ailment in which the main pumping chamber, the ventricles, enlarge and weaken as a result of which the heart’s ability to pump blood is greatly reduced.
- Other types of cardiomyopathy include hypertrophic (HCM) and restrictive (RCM) cardiomyopathies.
- Read at:http://www.thehindu.com/todays-paper/tp-features/tp-sci-tech-and-agri/novel-gene-mutation-causes-sudden-cardiac-death-in-indians/article6218816.ece